Brain Activity of Benzoate, a D-Amino Acid Oxidase Inhibitor, in Patients With Mild Cognitive Impairment in a Randomized, Double-Blind, Placebo Controlled Clinical Trial.

Int J Neuropsychopharmacol · 2021 · PMC8130199 · PMID 33406269

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Further, the MCI patients with increased ReHo in the orbital part of the inferior frontal gyrus (which is cytoarchitectonically most closely represented by Brodmann area 47) showed a trend of deteriorating into AD or remaining in MCI rather than reverting to a cognitively intact state ( Cai et al., 2018 ).

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