Breadth and function of antibody response to acute SARS-CoV-2 infection in humans.

PLoS Pathog · 2021 · PMC8130932 · PMID 33635919

Europe PMC DOI

hedged sentence

0.4500

closest p · 9.0× alpha

0.4500

boldest claim

The sentences

did not reach statistical significancep = 0.45not close (p > 0.1)

Those cross-reactive with SARS-CoV carried more nucleotide and amino acid substitutions than SARS-CoV-2-specific MAbs in their variable domains, but this trend did not reach statistical significance (Cross-reactive heavy 24±19 nt versus specific heavy 8±14 nt, p = 0.45; Cross-reactive heavy 13±10 aa versus specific heavy 5±8 aa, p = 0.45; two-tailed Mann-Whitney test; Fig 2D ).

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