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Short and dysfunctional telomeres protect from allergen-induced airway inflammation.

Aging Cell · 2021 · PMC8135011 · PMID 33942458

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Also, G3 Tert −/− mice showed increased dynamic compliance (Cdyn) compared to wild‐type mice after HDM exposure, although the difference did not reach statistical significance (Figure 2a,b ).

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In agreement with these findings, G3 Tert −/− total lung extracts, showed significantly decreased mRNA expression levels of the goblet cell hyperplasia markers Foxm1 , Spdef , and Muc5ac compared with wild‐type lungs, and this difference almost reached statistical significance in the case of Foxm1 (Figure 3v‐x ).

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