The α3 subunit of GABA_A receptors promotes formation of inhibitory synapses in the absence of collybistin.

In contrast, changes in the numbers of GFP–gephyrin microclusters in cells coexpressing GABA A R-α1 A317W (0.9 ± 1.6) or GABA A R-α2 A318W (4.4 ± 4.4) did not reach statistical significance, as compared with cells coexpressing GABA A R-α1 WT (0.9 ± 1.28) or GABA A R-α2 WT (1.3 ± 1.56), respectively ( Fig. 1 O ).

also in 111,027 other papers