More recently, we have shown that treatment with BafiertamTM (MMF), compared to its prodrug, Tecfidera ® (DMF), for 5 weeks in healthy subjects showed a trend for a reduction in incidence, severity, and duration of GI symptoms favoring MMF [ 11 ].
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Pharmacokinetics and Bioavailability of Monomethyl Fumarate Following a Single Oral Dose of Bafiertam™ (Monomethyl Fumarate) or Tecfidera<sup>®</sup> (Dimethyl Fumarate).
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