Conjugated equine estrogen used in postmenopausal women associated with a higher risk of stroke than estradiol.

Sci Rep · 2021 · PMC8144437 · PMID 34031535

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did not reach statistical significanceno p-value reported

In subgroup analysis, we found that the CEE group had a higher risk of IS than the E2 group (with hypertension, DM, hyperlipidemia, angina, COPD, and CAD, without heart failure and AF), although a few of the comparisons did not reach statistical significance.

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