The associations of the T1 and T2 SNPs with IgE levels were significant for the dominant model in adults ( p = 0.0047 and 0.0038, respectively), while in children, they showed a tendency toward significance with p = 0.0806 and 0.0729, respectively.
However, in the dominant model, the association with IgE levels did not reach statistical significance in controls or asthmatic patients ( p = 0.115 and 0.8174, respectively).
Interestingly, the V4 polymorphism showed a positive correlation, with passive smoking being a precipitating factor and showing borderline significance with absolute eosinophilia.