Barely Significant
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Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.

Nat Genet · 2021 · PMC8148035 · PMID 33398198

Europe PMCDOI
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hedged sentence
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closest p · 1.0× alpha
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nominally significantP < 0.05actually significant
Exceptions were nominally significant (P < 0.05) inverse associations (OR < 0.9) observed with variants at the KLK3 locus on chromosome 19 (rs76765083, OR = 0.71, P = 1.54×10 −39 and rs61752561, OR = 0.89, P=1.43×10 −4 ) and positive associations (OR > 1.1) observed with variant rs183373024 at 8q24 (OR = 1.14, P = 0.0047) and non-synonymous variant rs138708 ( NP_001186508.1 :p.Arg369Cys) in the SUN2 gene on chromosome 22 (OR = 1.12, P = 0.01) ( Supplementary Table 6 ).

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