Age-related differences of genetic susceptibility to patients with acute lymphoblastic leukemia.

Aging (Albany NY) · 2021 · PMC8148462 · PMID 33891562

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.2100

boldest claim

The sentences

marginally significantP = 0.07so close (0.05 < p ≤ 0.1)

In pediatric ALL patients, the novel Hispanic-specific ALL risk signal at ERG locus exhibited marginally significant association with ALL susceptibility in Chinese patients ( P = 0.07, OR = 1.18 [0.99-1.41]), and reached statistical significance in patients without common fusion ( P = 0.02, OR = 1.29 [1.04-1.61]), which has been validated in previous study [ 28 ].

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did not reach statistical significanceP = 0.21not close (p > 0.1)

Although association of rs7088318 at BMI - PIP4K2A locus with ALL susceptibility did not reach statistical significance in the whole patient cohort ( P = 0.21, OR = 1.11 [0.94-1.31]), risk allele of this SNP was enriched in B-ALL patients with no common fusions ( P = 0.05, OR = 1.21 [1.00-1.49]).

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