The Ratio of GrzB⁺ - FoxP3⁺ over CD3⁺ T Cells as a Potential Predictor of Response to Nivolumab in Patients with Metastatic Melanoma.

Kaplan–Meier PFS and overall survival (OS) curves showed a trend between the values of ratio (cut-off: −0.05) and the duration of response: patients with a low ratio (<−0.05) had lower PFS and OS compared with patients with a higher ratio (≥−0.05) ( p = 0.022 and p = 0.016, respectively) ( Figure 4 ). 4.

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