Barely Significant
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What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications.

J Med Chem · 2021 · PMC8154580 · PMID 33847110

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a clear trendno p-value reported
Overall, therefore, the data from the INN lists show a clear trend in increased MW.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.