Barely Significant
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Early constipation predicts faster dementia onset in Parkinson's disease.

NPJ Parkinsons Dis · 2021 · PMC8154963 · PMID 34039994

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Our data also suggest a similar trend for an association with faster motor progression to H&Y stage 3 and death, although these associations did not reach statistical significance in Cox regression modelling with correction for covariates.

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