Barely Significant
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Equity in clinical trials for HIV-associated cryptococcal meningitis: A systematic review of global representation and inclusion of patients and researchers.

PLoS Negl Trop Dis · 2021 · PMC8158913 · PMID 34043617

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an increasing trendno p-value reported
Primary outcomes were initially centred around clinical and microbiological markers, but in recent years, there has been an increasing trend towards mortality being the primary outcome.

also in 63,971 other papers

a significant trendno p-value reported
With the change in location from HICs to LMICs, there has been a significant trend for authors to be nonnationals of the country where research is performed, particularly in first and senior author positions.

also in 9,775 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.