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SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.

Heliyon · 2021 · PMC8159709 · PMID 34075347

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We characterized the cytotoxic potential of CD8 + T cells based on granzyme A and perforin levels and found that there was a tendency of decreased granzyme A expression in mild and moderate patients compared with HC ( Figure 6 b), however, it did not reach statistical significance.

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