Broad auto-reactive IgM responses are common in critically ill patients, including those with COVID-19.

Cell Rep Med · 2021 · PMC8160082 · PMID 34075365

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did not reach statistical significanceno p-value reported

The presence of auto-IgM and auto-IgA antibodies in COVID ICU patients was significantly increased compared with COVID non-ICU patients and healthy controls, while increased presence of auto-IgG was suggested, but did not reach statistical significance ( Figure S1 G).

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