Long-Term Exposure to Nanosized TiO₂ Triggers Stress Responses and Cell Death Pathways in Pulmonary Epithelial Cells.

Cells exposed to TiO 2 for 13 weeks showed a trend of shorter telomere length at both doses compared with Ctrl ( Figure 4 ).

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Similarly, two other studies have shown that the interference of nanomaterials with flow cytometry assays is dose-dependent and is more likely to be significant at higher concentrations [ 50 , 51 ].

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