Inhibition of Maternal-to-Fetal Transfer of IgG Antibodies by FcRn Blockade in a Mouse Model of Arthrogryposis Multiplex Congenita.

Neurol Neuroimmunol Neuroinflamm · 2021 · PMC8161539 · PMID 34045306

Europe PMC DOI

hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

failed to reach statistical significancep = 0.085so close (0.05 < p ≤ 0.1)

Treatment with 4470 was also associated with a numerical increase in the percentage of embryos showing spontaneous movements (mainly an inspiratory breathing gasp after dissection of the embryos from the uteri) after AMC-IgG exposure, but this failed to reach statistical significance ( p = 0.085, unpaired t test [2 tailed], Cohen d = 1.1; figure 2E ).

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