Macrocyclization of bis-indole quinolines for selective stabilization of G-quadruplex DNA structures.

Chem Sci · 2020 · PMC8162405 · PMID 34094311

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a clear trendno p-value reported

A clear trend in the size of the macrocycles with the linker in position 6 ( 14a1–4 ) was observed where the smaller macrocycles more effectively stabilized the G4 structures.

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