Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo.

Nat Commun · 2021 · PMC8163834 · PMID 34050192

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showed a trendno p-value reported

Some skeletal muscles showed a trend in decreasing mutant mtDNA (TA, gastrocnemius at 24 weeks PI), but results did not reach significance (Fig. 4b ).

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