The Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas.

Front Cell Dev Biol · 2021 · PMC8165280 · PMID 34079802

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

failed to reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Although the difference failed to reach statistical significance, the expression of B7H3 tended to be lower in IDH-mutated GBM (n = 7) compared to that in IDH-WT GBM ( n = 142) according to TCGA dataset analysis ( p = 0.07, Figure 1A ).

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