An update on targeted therapies in systemic sclerosis based on a systematic review from the last 3 years.

Arthritis Res Ther · 2021 · PMC8168022 · PMID 34074331

Europe PMC DOI

hedged sentences

0.0579

closest p · 1.2× alpha

0.0980

boldest claim

The sentences

almost significantp = 0.0579so close (0.05 < p ≤ 0.1)

A further and almost significant improvement was observed at 48 weeks in TCZ-treated patients compared to placebo (− 3.55, 95% CI − 7.23 to 0.12; p = 0.0579).

also in 1,858 other papers

did not reach statistical significancep = 0.098so close (0.05 < p ≤ 0.1)

The improvement in the mRSS was higher in TCZ patients compared to placebo (− 6.1 versus − 4.4) but it did not reach statistical significance (p = 0.098).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.