Substrate Stiffness Regulates Cholesterol Efflux in Smooth Muscle Cells.

Front Cell Dev Biol · 2021 · PMC8168435 · PMID 34084769

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a significant trendno p-value reported

Among the stiffness range we tested (1, 8, 20, 40, 100 kPa), the cholesterol accumulation in SMCs on both softer (1 and 8 kPa) and harder substrates (100 kPa) demonstrated a significant trend of increase compared to those on substrates with moderate stiffness (20 and 40 kPa).

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