Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene.

Genomic location of top SNPs for affective temperament phenotypes Proportion of intronic SNPs was nominally significant in case of all five affective temperament phenotypes, and with the exception of anxious temperament phenotype, in case of the other four temperament phenotypes proportion of noncoding RNA intronic SNPs was also nominally significant (Fig. 3 ).

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