Inhibition of mTOR signaling did not prevent stimulation of neurogenesis by IGF1, but appeared to augment the number of posttrauma-proliferated cells within the GCL that committed to a neuronal fate in IGFtg mice, although this increase did not reach statistical significance ( p = 0.062, Figure 5B ).
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IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR.
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