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Left ventricular global longitudinal strain in predicting CRT response: one more J-shaped curve in medicine.

Heart Vessels · 2021 · PMC8175293 · PMID 33550426

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showed a trendno p-value reported
Moreover, CRT might be harmful, in the European REVERSE substudy, the NYHA class I patients showed a trend toward worsened HF clinical composite response [ 33 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.