Evaluation of Intra-Articular Amikacin Administration in an Equine Non-inflammatory Joint Model to Identify Effective Bactericidal Concentrations While Minimizing Cytotoxicity.

CRP concentrations increased in horses treated with 500 mg amikacin compared to all other treatments at 8 and 24 h, which did not reach statistical significance (concentration effect overall, p = 0.08) ( Figure 3 ).

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