More recently, single-nucleus RNA sequencing in Alzheimer disease and control prefrontal cortex has revealed that among the differentially expressed genes, there is a strong trend toward a general repression of gene expression in in neurons in Alzheimer disease ( 11 ).
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Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau.
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