Most importantly, the comparison of the miRNA expression profiles revealed a clear trend for miRNAs decreased in E2F1 knockdown cells to also be decreased in Salmonella -infected cells (Fig. 1b ), with 144 (26% of total; 56% of Salmonella downregulated) miRNAs downregulated in both conditions.
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Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected and bystander cells.
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