Reprogramming epiblast stem cells into pre-implantation blastocyst cell-like cells.

We prepared our scRNA-seq samples with Seurat's SCTransform ( Butler et al., 2018 ) and found a clear trend of three regions of cells on day 5 that clustered closely to similar expanded surrounding regions on day 7 ( Figure 2 C) across comparable ranges of features and counts with control cells ( Figure S2 C).

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