Increased glycolysis is an early consequence of palmitate lipotoxicity mediated by redox signaling.

Redox Biol · 2021 · PMC8187254 · PMID 34102573

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Palmitate-treated cells (dark columns) showed a trend toward an increase in H 2 O 2 release with all substrates (2-way ANOVA, FA*Inhibitor interaction, p = 0.06).

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highly significantno p-value reported

However, and quite surprisingly, palmitate promoted a highly significant increase in extracellular acidification rates (ECARs; Fig. 3 B), which were measured in parallel by extracellular flux analysis.

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