Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.

Nat Commun · 2021 · PMC8187652 · PMID 34103493

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Accordingly, our BA signature also correlated with the shorter survival of relapsing patients and showed a trend towards an increased frequency of peritoneal disease upon relapse (Fig. 3f , Supplementary Fig. 3d ), consistent with the pattern of metastatic spread in patients with rCRCs 12 , 13 .

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