Finally, HDAC9 transcript levels were downregulated in RA of pAF subjects (−65%, p = 0.046), whereas numerical reduction of LA HDAC9 mRNA by 45% did not reach statistical significance ( p = 0.061) (Figure 4n,p ).
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Differential regulation of K<sub>Ca</sub> 2.1 (KCNN1) K<sup>+</sup> channel expression by histone deacetylases in atrial fibrillation with concomitant heart failure.
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