13 The first randomized control trial comparing outcomes of MMS versus serial excision for the treatment of primary and recurrent facial BCC found a trend toward lower recurrence rates with MMS relative to SE for both primary and recurrent lesions but these findings did not reach statistical significance. 14 Subsequent 5-year 18 and 10-year 12 updates to this study found significantly lower rates of recurrence at both time points when MMS was used to treat recurrent facial BCC lesions.
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