Effects of variation in P2RX7 on current depressive symptoms: Main effects and interaction with childhood adversities (CHA) and recent life events (RLE) Our statistical analyses did not identify any SNPs with a nominally significant main effect on current depression (BSI-depression) thus clumps could not be identified.
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P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms.
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