A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.

Of the 236 prefrontal cortex DMPs, 92% (217 probes) were nominally significant ( P < 0.05) in the temporal gyrus, of which 12% (28 probes) were Bonferroni significant, whilst 9% (22 probes) were nominally significant in the entorhinal cortex, with 1% (3 probes) reaching Bonferroni significance (Fig. 1b ).

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