Barely Significant
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Early changes in the circulating T cells are associated with clinical outcomes after PD-L1 blockade by durvalumab in advanced NSCLC patients.

Cancer Immunol Immunother · 2021 · PMC8195930 · PMID 33420629

1
hedged sentence
0.0750
closest p · 1.5× alpha
0.0750
boldest claim

The sentences

showed a trendp = 0.075so close (0.05 < p ≤ 0.1)
After accounting for patient demographic and clinical characteristics, the multivariable CPH model showed that increased clonality showed a trend toward decreased OS (HR = 2.79 with 95% CI [0.90, 8.66], p = 0.075), though not statistically significant.

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