Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury.

Finally, samples from a third cohort (optifast) of obese individuals (BMI > 34 kg/m 2 , 29–65 years, n = 8) undergoing a 3-month formula diet with the fixed amount of 800 kcal/d to reach weight-loss showed a trend toward higher AEA levels after CR ( p -value: 0.1296) ( Figure 4 C).

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