Epithelial-Mesenchymal Transition (EMT) Induced by TGF-β in Hepatocellular Carcinoma Cells Reprograms Lipid Metabolism.

Int J Mol Sci · 2021 · PMC8197297 · PMID 34073989

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Confirming this hypothesis, levels of monoacylglycerols and diacylglycerols were in general decreased in TβT-Hep3B, being clearly significant in some cases, such as palmitoleoyl-oleoyl-glycerol or palmitoyl-linoleoyl-glycerol ( Supplementary Table S1 ), and the expression of LIPE (Lipase E or hormone-sensitive lipase) was increased in TβT-Hep3B cells (2.94 fold increase, p = 0.07).

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