tended towards significancep = 0.086
In multivariate analysis (Wald test; Table 2 ), two variables (pN and TN subtype) remained significant, whereas the 70-gene signature tended towards significance ( p = 0.086), and the prognostic value of XIAP was maintained (HR = 1.67, 95%CI 1.20–2.31, p = 2.07 × 10 −3 , Wald test), suggesting independent prognostic value.