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Co-administration of obeticholic acid and simvastatin protects against high-fat diet-induced non-alcoholic steatohepatitis in mice.

Exp Ther Med · 2021 · PMC8200799 · PMID 34149876

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Furthermore, the combination of OCA and SIM appeared to exhibit a stronger effect than OCA alone, but the difference between the HFD + OCA and HFD + OCA + SIM groups did not reach statistical significance.

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