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Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses.

Nat Commun · 2021 · PMC8206133 · PMID 34131120

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The numbers of CD45 + leukocytes infiltrated into B16–F10 tumors were higher in Ppm1d Fes-cre mice compared with Ppm1d fl/fl mice, but the differences did not reach statistical significance (Fig. 2b ).

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