In addition, although the sex variable did not reach statistical significance ( p = 0.075) in the multivariate analysis, we still added it into the nomogram, considering that several researches have reported a relationship between sex and LS. 19 , 20 Moreover, we found that patients with MSH6 alone deficiency had the highest prevalence (60.0%) of LS and had the greatest probability (35%) to be microsatellite stability (MSS) or microsatellite instability-low (MSI-L).
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Development and external validation of a novel nomogram for screening Chinese Lynch syndrome: based on a multicenter, population study.
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