Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta-analysis.

10 , 12 , 13 , 15 , 16 , 17 , 19 , 20 , 22 Four studies suggested positive correlation, but the results did not reach statistical significance. 9 , 11 , 14 , 21 Only one study did not demonstrate positive correlation, although the study had a small number of CIED infection events. 18 In subgroup analysis, there is a slightly stronger association between postimplantation hematoma and risk of CIED infection in multi‐center studies when compared to single‐center studies.

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