New evaluation methods of read mapping by 17 aligners on simulated and empirical NGS data: an updated comparison of DNA- and RNA-Seq data from Illumina and Ion Torrent technologies.

Bowtie2 and STAR, whose median of percent relative error fell below 50% after 20% of resampling rate; (3) BWA-MEM, BWA, GEM, Hisat2, Magic-BLAST, Minimap2, Segemehl, Subread and TopHat2 that reached the 50% of median of percent relative error at around 15 resampling percentage; (4) Novoalign, which showed a trend very similar to group four, but with the median of percentage error under 50% already at 10% of resampling.

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