Genetic associations for two biological age measures point to distinct aging phenotypes.

Aging Cell · 2021 · PMC8208797 · PMID 34038024

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0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

marginally significantp = 0.058so close (0.05 < p ≤ 0.1)

Similarly, e2e2 and e2e3 showed a trend toward increased PhenoAge, with e2e2 being marginally significant ( p = 0.058) and e2e3 not significant ( p = 0.291).

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showed a trendno p-value reported

Overall, the three e4 genotypes showed a trend toward decreased PhenoAge, similar to what was observed in UKB, although only e2e4 significantly differed from e3e3 ( p = 0.039), while e3e4 was marginally decreased ( p = 0.054), and e4e4 was not significant ( p = 0.912).

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