Rate of Freeze Impacts the Survival and Immune Responses Post Cryoablation of Melanoma.

Front Immunol · 2021 · PMC8210778 · PMID 34149738

Europe PMC DOI

hedged sentences

0.0760

closest p · 1.5× alpha

0.0760

boldest claim

The sentences

a clear trendP =0.076so close (0.05 < p ≤ 0.1)

Of note, a clear trend was observed with decreased PD1 + CD4 + Tregs at day 8 post ablation in TDLN in both slow and fast freeze groups ( P =0.076 and P =0.082, respectively Supplementary Table 2 ).

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an increasing trendno p-value reported

Intriguingly, at day 8 post ablation, eosinophils were significantly increased in the fast freeze group, and exhibited an increasing trend in the slow freeze group ( Figure 4D ).

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