Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming.

PLoS Biol · 2021 · PMC8211187 · PMID 34138843

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an elevated trendno p-value reported

Finally, quantitative RT-PCR (qRT-PCR) analysis showed that in the cerebral CTX, there was a significant increase in IL-6 and TNF-α mRNA levels and an elevated trend but lack of significance of IL-1β in e Adora2b −/− mice following hypoxia treatment.

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showed a trendno p-value reported

Meanwhile, double-positive staining of Iba1 and CD68 showed a trend toward microglia activation (without significance) in e Adora2b −/− mice ( Fig 5C and 5G ).

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