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IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells.

J Immunother Cancer · 2021 · PMC8212411 · PMID 34140316

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Notably, met-high tumors exhibited the highest percentage of LSK cells in the BM niche of B16 melanoma, but such differences did not reach statistical significance in the breast cancer model.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.