Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1.

Furthermore, there was a trend towards a higher frequency of PD-1 + cells in TINK compared to PBNK that did not reach statistical significance ( Figure 4M ), while the amount of expression of MHC-I ( Figure 4N ) was similar in both NK cell compartments.

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