At the end of week 48, although there was a trend toward higher ACR20 and ACR70 in the MTX plus 99 Tc-MDP combination group than in the MTX monotherapy group, the difference did not reach statistical significance.
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A double-blind, double-dummy, randomized controlled, multicenter trial of 99Tc-methylene diphosphonate in patients with moderate to severe rheumatoid arthritis.
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